With Peter Parker's ONE MOMENT IN TIME behind him and Mary Jane back in his life, Spidey finds himself ready for a new start...but the various threads of his life since his BRAND NEW DAY are about to crash together violently. When Norman Osborn's baby is born...every villain on the planet wants the first ever strain of pure Goblin blood, leaving Spider-Man's friends and family exposed to a Sinister plan that threatens to bring down every strand or Peter's life that's been stitched together carefully over the past few years.