Nitric Oxide in Health and Disease

Description

Nitric oxide has a tantalising role in health and disease: whilst many of its wide-ranging effects are well known, there remains much more to explore and to learn about the interactions of this fascinating molecule in physiological and pathophysiological processes. The volume reviews the myriad of effects of nitric oxide: as a chemical messenger in the central nervous system, peripheral nervous system, immune system and cardiovascular system. Furthermore, it provides a very practical introduction to the procedures and experimental protocols necessary to work with and study nitric oxide and its synthesing enzyme, nitric oxide synthase, in the laboratory. In this respect the volume is unique, providing as it does a complete single-volume review of the role of nitric oxide in health and disease, and a very practical introduction to the methods and protocols involved in this intriguing and active area of biomedical research.

'... exceptional, standing out by successfully covering all aspects of the biology of nitric oxide in a single volume ... an excellent choice for both experts and beginners looking either for a source of reference or a starting point ... well written, up-to-date and clinically useful'. Anwar R. Baydoun, Nature Medicine ' ... a unique and useful approach ... provides an excellent introduction to this rapidly developing field'. Steven R. Vincent, Trends in Neurosciences '... an excellent choice for both experts and beginners looking either for a source of reference or a starting point. It provides a state-of-the-art overview of all aspects of nitric oxide research, is well written up-to-date and clinically useful'. Nature Medicine 'This reference will be useful for those scientists who wish to explore the possibility that NO plays a role in the disease in which they are interested and are looking for a 'one stop shopping' collection of ideas and protocols to get them started.' Stephanie L. James, Parasitology Today